Recent advancements have introduced innovative techniques for detecting COVID-19, improving speed, accuracy, and convenience. Here are some notable methods:

Super-Resolution Microscopy: Researchers at Stanford University developed a technique using fluorescent molecules to achieve nanoscale imaging of SARS-CoV-2 within cells. This approach reveals viral RNA and replication structures with unprecedented clarity, offering insights for drug development and virus behavior studies.

Real-Time Airborne Virus Detection: A device by Washington University in St. Louis can detect airborne SARS-CoV-2 particles within five minutes. Using a cyclone sampler and biosensors with llama-derived nanobodies, it captures and identifies virus particles from the air. This technology has applications in public spaces like airports and hospitals, providing near-instant feedback on virus presence.

CRISPR-Based Diagnostics: Tools like SHERLOCK and DETECTR employ CRISPR technology for COVID-19 detection, targeting specific genetic sequences of the virus. These methods are rapid and highly sensitive, offering results comparable to PCR testing but in a shorter time.

Wearable Biosensors: Some devices can continuously monitor physiological changes, such as respiratory rate or temperature, for early signs of infection. Advances in nanotechnology have made these biosensors more effective and accessible.

These advancements highlight the integration of molecular biology, engineering, and nanotechnology to enhance COVID-19 detection, which may also be adapted for other pathogens in the future.